Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis

“De novo mutations identified by whole-genome sequencing implicate chromatin modifications in obsessive-compulsive disorder” Guan Ning Lin, Weichen Song, Weidi Wang, Pei Wang, Huan Yu, Wenxiang Cai, Xue Jiang, Wu Huang, Wei Qia, Yucan Chen, Miao Chen, Shunying Yu, Tingting Xu, Yumei Jiao, Qiang Liu, Chen Zhang, Zhenghui, Qing Fan, Jue Chen, Zhen Wang

“PANS/PANDAS: Clinical Experience in IVIG Treatment and State of the Art in Rehabilitation Approaches” Piero Pavone, Raffaele Falsaperla, Giovanni Cacciaguerra, Annamaria Sapuppo, Rita Chiaramonte, Riccardo Lubrano, Giulia Messina, Sarah Sciuto, Luca Sabino, Salvatore Cocuzza, Antonino Maniaci , Alessandra Fontana, Lidia Marino, Claudia Oliva, Maria Grazia Pappalardo, Michele Vecchio “Immunological causes of obsessive-compulsive disorder: is it […]

“Autoimmune encephalitis in children: clinical phenomenology, therapeutics, and emerging challenges” Russell C Dale 1, Mark P Gorman, Ming Lim “Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections” Jennifer L Chain, Kathy Alvarez, Adita Mascaro-Blanco, Sean Reim, Rebecca Bentley, Rebecca Hommer, Paul Grant, James F Leckman, […]

“Mannose-Binding Lectin 2 Gene Polymorphism in PANDAS Patients” Gonca Gül Çelik 1, Didem Arslan Taş 2, Ayşegül Yolga Tahiroglu 1, Eren Erken 2, Gülşah Seydaoğlu 3, Perihan Çam Ray 1, Ayşe Avci 1 “Clinical features of paediatric acute-onset neuropsychiatric syndrome: findings from a case– control study” Eva Hesselmark and Susanne Bejerot “A Pediatric Infectious Disease […]

Treatment of PANDAS and PANS: a systematic review. Allergic Diseases and Immune-Mediated Food Disorders in Pediatric Acute-Onset Neuropsychiatric Syndrome. Pediatric acute-onset neuropsychiatric syndrome (PANS) misdiagnosed as autism spectrum disorder. Continued Presence of Period Limb Movements During REM Sleep in Patients With Chronic Static Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS). Individualized Immunological Data for Precise Classification of […]

Impact of Immunoglobulin Therapy in Pediatric Disease: a Review of Immune Mechanisms. PANDAS: Baseline Immunoglobulin Levels Predict Achievement of Remission at One Year Following IVIg Therapy. Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells. Post-Streptococcal Autoimmune Sequelae: Rheumatic Fever and Beyond. Effect of Early and Prophylactic Nonsteroidal Anti-Inflammatory Drugs on Flare […]

Post-infectious autoimmune disorders: Sydenham’s chorea, PANDAS and beyond. Characterization of the pediatric acute-onset neuropsychiatric syndrome phenotype. PANDAS and Comorbid Kleine–Levin Syndrome. Disordered Eating and Food Restrictions in Children with PANDAS/PANS. Cefdinir for Recent-Onset Pediatric Neuropsychiatric Disorders: A Pilot Randomized Trial. The usefulness of immunotherapy in pediatric neurodegenerative disorders: A systematic review of literature data. Therapeutic […]

Clinical Evaluation of Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): Recommendations from the 2013 PANS Consensus Conference. A new clinical feature associated with familial early-onset of dystonic-guttural tics: An unusual diagnosis of PANDAS. Behavioral and neural effects of intra-striatal infusion of anti-streptococcal antibodies in rats. Gilles de la Tourette Syndrome Caused by Mycoplasma pneumoniae Successfully […]

Brain Human Monoclonal Autoantibody from Sydenham Chorea Targets Dopaminergic Neurons in Transgenic Mice and Signals Dopamine D2 Receptor: Implications in Human Disease1.